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Division of Analysis

Randomized, double-blind, placebo controlled evaluation of monthly WR238605 (Tafenoquine) for prophylaxis of Plasmodium falciparum and Plasmodium vivax in RTA soldiers.

         Military personnel routinely undergo screening and confirmatory tests of drug abuse, primarily morphine, amphetamine and marijuana. Surveillance reveals a shift from the use of morphine narcotics to amphetamine; however, positive cases remain at less than two percent.

          Research and laboratory support are provided to assess environmental, clinical and occupational exposures to potential hazards. Active investigations include monitoring the water supply for quality and contaminants, evaluating health problems in workers exposed to toxic chemicals in RTA industrial plants, studies of cyanobacterial toxins in water resources in army units and determination of vitamin, electrolyte or antimalarial drugs levels in biological fluids.

          Health promotion has a high priority and clinical laboratory testing is accomplished to screen the military population for nutritional, genetic, metabolic, or environmentally induced diseases to effect early detection and allow prompt intervention. Studies of the herbal effects on biochemistry values are also conducted.

          The seroprevalence of antibody to leptospirosis and risk factors are determined in Thai military recruits. Collaborative studies involving zoonotic and vector-borne diseases are ongoing. Wild and indigenous animals are monitored for scrub typhus and leptospirosis. Animal studies have been conducted to determine the efficacy of therapeutics in treating scrub typhus and nematode parasites.

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