TABLE OF CONTENTS
Prologue H.E. Lieutenant General Jesus Vargas
Secretary General, SEATO
I
Rear Admiral Samrit Jatinandana, MC, RTN
Director General
SEATO Medical Research Project
II
Introduction Colonel Leslie B. Altstatt, MC
Director
US Army Medical Component, SEATO
III
Virus Diseases of Man and Animals
1
The Ecology of Japanese Encephalitis Virus Infection in Chiangmai
3
A Study of Japanese Encephalitis Virus in Chiangmai Valley: The Role of
Small Wild Vertebrates in Virus Transmission
16
Zoonotic Aspects of JEV Infection Outside the Chiangmai Valley
26
Experimental Infections of the Thai Domestic Animals with Japanese
Encephalitis Virus
27
Experimental Transmission of Japanese Encephalitis Virus by Culex
fuscocephala
36
JE Virus Recovery After High Speed Centrifugation of Presumably Infected
Mosquito Pools
41
The Sensitive Host for Recovery of Japanese Encephalitis Virus (JEV)
43
Group B Arbovirus Serology: Search for Humoral Specificity
46
Immunoglobulin Response and Viremia in Dengue Vaccinated Gibbons
Repeatedly Challenged with Japanese Encephalitis Virus
54
Evaluation of the Antigenic Potency of Biken JEV Vaccine in Adults
62
Isolation of Ingwavuma Virus and Study of Ingwavuma Antibody
Prevalence in the Chiangmai Valley
66
Pathogenesis of Dengue Shock Syndrome
75
Isolation of Dengue Virus from Dengue Hemorrhagic Fever Patients
88
Cellular Immunity in Dengue Infections
93
Infection and Malnutrition: Immune Function in children with Protein-
Calorie and Vitamin A Malnutrition
95
Isolation and Characterization of Influenza A Viruses from Korat
103
The Study of Coronavirus OC43 Infection
104
Reservoirs of Rabies in Thailand
108
Identification of Vertebrate Hosts of Ectoparasites in Thailand
111
The Prevalence of Hepatitis-Associated Antigen (HAA) Among Thais
Hospitalized with Acute Hepatitis
117
Study of Hepatitis in a Pediatric Outpatient Department
121
Hepatitis-Associated Antigen (HAA) in American Personnel with Acute
Hepatitis in the Republic of Vietnam
128
The Epidemiology of Hepatitis-Associated Antigen (HAA) in a Defined
Urban Population I. Prevalence Survey
129
Observations of HAA in A Blood Donor/Recipient System in Thailand
140
Comparison of the Sensitivity of Complement Fixation (CF) Test and
Immunoelectroosmophoresis (IEOP) for Detection of Hepatitis B
156
An Automatic Data Processing System for the Blood Bank Project
158
Bacterial Diseases of Man and Animal
165
Vibrio parahaemolyticus in Thailand
167
Vibrio parahaemolyticus in Pediatric Outpatient Diarrhea Patients
176
The Infant Rabbit as a Model of Pathogenicity for Vibrio parahaemolyticus
178
The Etiology of the Non-Luetic Soft Chancre
182
Neisseria gonorrheae Infections of the Premenarcheal Female
185
Serum Antibiotic Levels Associated with Gonorrheae in Females
189
Minimum Inhibitory Concentration (MIC) of Penicillin G and Oxytetracycline
to Neisseria gonorrheae
191
Clinical Evaluation of Co-trimoxazal (Trimethroprim/Sulfamethylthiazole)
and Furazolidone in Treatment of Shigellosis in Children
193
Anaerobic Bacteriology
195
Diarrheal Diseases
201
Mycotic Diseases
206
Mycobacterium Tuberculosis
208
Bacterial Diseases of Domestic Animals Native to Thailand
210
Distribution and Ecology of Ectoparasites of Vertebrates in Southeast Asia
212
Survey to Estimate Significance of Certain Zoonotic Diseases and Their
Military Importance in Thailand
214
Parasitic Diseases of Man and Animal
223
Viability of Plasmodium falciparum Frozen in Liquid Nitrogen in the
Presence of Dimethyl Sulfoxide
225
Malaria Drug Screening Study
227
Comparative Pathophysiology of Strains of E.histolytica
228
Immunodiagnosis of Parasitic infections
230
Chemotherapy of Gnathostomiasis
231
Studies of New Experimental Hosts Life Cycles and Modes of Transmission
of Gnathostomes
240
Strongyloidiasis in the Gibbon
242
Metabolic Diseases of Man and animal
245
Gibbon Menstrual Cycle and Breeding Study
247
Saticylate Toxicity in Monkeys
250
Leukemia in the Gibbon
251
Hepatic Function in Cerebral Malaria
252
Gibbon Growth and Development Study
254
Laboratory Animal Disease in Thailand: Its Occurrence and Importance
to Comparative Medicine
255
Psychiatry and behavioral Studies
261
A Follow Up Study of Japanese Encephalitis in Northern Thailand
263
Prediction of Drug Abuse in Servicemen-Phase I
264
A Study of the Interface Between American Soldiers and the Thai
Community and its Effects on Drug Taking Behavior
266
Field Studies in Malaria
269
Minocycline and Tetracycline Treatment of Acute Falciparum Malaria in
Thailand
271
Quinine-Tetracycline and Quinine-Bactrim Treatment of Acute Falciparum
Malaria in Thailand
273
Quinine Treatment of Acute Falciparum Malaria in Central Thailand
279
A Comparative Evaluation of Sulfalene-Trimethoprlm and
Fanasil-Pyrimethamine Against Falciparum Malaria in Thailand
282
Investigations of In vivo and In vitro Chloroquine Sensitivity of
P. falciparum in Yala Province
286
Investigations of the Fluorescent Spot Test for Erythrocyte
Glucose-6-Phosphate Dehydrogenase Deficiency in Southeast Thailand
292
Evaluation of In vitro Drug Sensitivity of Human P. falciparum
by Incorporation of Radioactive Isoleucine
297
Hemolytic Activity in Human Malaria Infections
308
Malaria Field Study Khok Salung, Lopburi
312
Plasmodium falciparum Infection Rates in Normal and Enzyme-Deficient
Erythrocytes of G-6-PD Deficient Heterozygotes
318
Longitudinal Malaria Studies in Rural Northeast Thailand
319
Ecology of Malaria Vectors
327
Effect of Sulphamethoxazole-trimethoprim on the Viability of
P. falciparum Gametocytes
336
Mosquito Fauna of Thailand
337
A Review of the Drug Sensitivity of Plasmodium falciparum in Thailand
338
Index of Principal Investigators
349