TABLE OF CONTENTS

 

Prologue                                               H.E. Lieutenant General Jesus Vargas

Secretary General, SEATO

I

                                                            Rear Admiral Samrit Jatinandana, MC, RTN

Director General

SEATO Medical Research Project

II

Introduction                                          Colonel Leslie B. Altstatt, MC

Director

US Army Medical Component, SEATO

III

 

 

Virus Diseases of Man and Animals

1

            The Ecology of Japanese Encephalitis Virus Infection in Chiangmai

3

A Study of Japanese Encephalitis Virus in Chiangmai Valley: The Role of

Small Wild Vertebrates in Virus Transmission

16

            Zoonotic Aspects of JEV Infection Outside the Chiangmai Valley

26

Experimental Infections of the Thai Domestic Animals with Japanese

Encephalitis Virus

27

Experimental Transmission of Japanese Encephalitis Virus by Culex

fuscocephala

36

JE Virus Recovery After High Speed Centrifugation of Presumably Infected

Mosquito Pools

41

            The Sensitive Host for Recovery of Japanese Encephalitis Virus (JEV)

43

            Group B Arbovirus Serology: Search for Humoral Specificity

46

            Immunoglobulin Response and Viremia in Dengue Vaccinated Gibbons

Repeatedly Challenged with Japanese Encephalitis Virus

54

            Evaluation of the Antigenic Potency of Biken JEV Vaccine in Adults

62

            Isolation of Ingwavuma Virus and Study  of Ingwavuma Antibody

Prevalence in the Chiangmai Valley

66

            Pathogenesis of Dengue Shock Syndrome

75

Isolation of Dengue Virus from Dengue Hemorrhagic Fever Patients

88

Cellular Immunity in Dengue Infections

93

Infection and Malnutrition: Immune Function in children with Protein-

Calorie and Vitamin A Malnutrition

95

            Isolation and Characterization of Influenza A Viruses from Korat

103

            The Study of Coronavirus OC43 Infection

104

            Reservoirs of Rabies in Thailand

108

            Identification of Vertebrate Hosts of Ectoparasites in Thailand

111

            The Prevalence of Hepatitis-Associated Antigen (HAA) Among Thais

Hospitalized with Acute Hepatitis

117

            Study of Hepatitis in a Pediatric Outpatient Department

121

            Hepatitis-Associated Antigen (HAA) in American Personnel with Acute

Hepatitis in the Republic of Vietnam

128

            The Epidemiology of Hepatitis-Associated Antigen (HAA)        in a Defined

Urban Population  I. Prevalence Survey

129

            Observations of HAA in A Blood Donor/Recipient System in Thailand

140

Comparison of the Sensitivity of Complement Fixation (CF) Test and

Immunoelectroosmophoresis (IEOP) for Detection of Hepatitis B

156

            An Automatic Data Processing System for the Blood Bank Project

158

 

 

Bacterial Diseases of Man and Animal

165

            Vibrio parahaemolyticus in Thailand

167

            Vibrio parahaemolyticus in Pediatric Outpatient Diarrhea Patients

176

            The Infant Rabbit as a Model of Pathogenicity for Vibrio parahaemolyticus

178

The Etiology of the Non-Luetic Soft Chancre

182

Neisseria gonorrheae Infections of the Premenarcheal Female

185

Serum Antibiotic Levels Associated with Gonorrheae in Females

189

Minimum Inhibitory Concentration (MIC) of Penicillin G and Oxytetracycline

to Neisseria gonorrheae

191

Clinical Evaluation of Co-trimoxazal (Trimethroprim/Sulfamethylthiazole)

and Furazolidone in Treatment of Shigellosis in Children

193

Anaerobic Bacteriology

195

Diarrheal Diseases

201

Mycotic Diseases

206

Mycobacterium Tuberculosis

208

Bacterial Diseases of Domestic Animals Native to Thailand       

210

Distribution and Ecology of Ectoparasites of Vertebrates in Southeast Asia       

212

Survey to Estimate Significance of Certain Zoonotic Diseases and Their

Military Importance in Thailand

214

 

 

 

Parasitic Diseases of Man and Animal

223

            Viability of Plasmodium falciparum Frozen in Liquid Nitrogen in the

Presence of Dimethyl Sulfoxide

225

            Malaria Drug Screening Study

227

            Comparative Pathophysiology of Strains of E.histolytica

228

            Immunodiagnosis of Parasitic infections

230

            Chemotherapy of Gnathostomiasis

231

            Studies of New Experimental Hosts Life Cycles and Modes of Transmission

of Gnathostomes

240

            Strongyloidiasis in the Gibbon

242

 

 

Metabolic Diseases of Man and animal

245

            Gibbon Menstrual Cycle and Breeding Study

247

            Saticylate Toxicity in Monkeys

250

            Leukemia in the Gibbon

251

            Hepatic Function in Cerebral Malaria   

252

            Gibbon Growth and Development Study

254

            Laboratory Animal Disease in Thailand: Its Occurrence and Importance

to Comparative Medicine

255

 

 

Psychiatry and behavioral Studies

261

            A Follow Up Study of Japanese Encephalitis in Northern Thailand

263

            Prediction of Drug Abuse in Servicemen-Phase I

264

            A Study of the Interface Between American Soldiers and the Thai

Community and its Effects on Drug Taking Behavior

266

 

 

Field Studies in Malaria

269

Minocycline and Tetracycline Treatment of Acute Falciparum Malaria in

Thailand

271

 

 

 

Quinine-Tetracycline and Quinine-Bactrim Treatment of Acute Falciparum

Malaria in Thailand

273

            Quinine Treatment of Acute Falciparum Malaria in Central Thailand

279

A Comparative Evaluation of Sulfalene-Trimethoprlm and

Fanasil-Pyrimethamine Against Falciparum Malaria in Thailand

282

            Investigations of In vivo and In vitro Chloroquine Sensitivity of

P. falciparum in Yala Province

286

            Investigations of the Fluorescent Spot Test for Erythrocyte

Glucose-6-Phosphate Dehydrogenase Deficiency in Southeast Thailand

292

            Evaluation of In vitro Drug Sensitivity of Human P. falciparum

by Incorporation of Radioactive Isoleucine

297

            Hemolytic Activity in Human Malaria Infections

308

            Malaria Field Study Khok Salung, Lopburi

312

            Plasmodium falciparum Infection Rates in Normal and Enzyme-Deficient

Erythrocytes of G-6-PD Deficient Heterozygotes

318

            Longitudinal Malaria Studies in Rural Northeast Thailand

319

            Ecology of Malaria Vectors

327

            Effect of Sulphamethoxazole-trimethoprim on the Viability of

P. falciparum Gametocytes

336

            Mosquito Fauna of Thailand

337

            A Review of the Drug Sensitivity of Plasmodium falciparum in Thailand

338

Index of Principal Investigators

349