TABLE OF CONTENTS
Introduction Air Vice Marshal Sithibun Purnaveja, MC, RTAF
Director General
Armed Forces Research Institute of Medical Sciences
Introduction LTC Herbert E. Segal, MC, USA
Director, US Army Medical Component
TROPICAL AND SUBTROPICAL DISEASES
A Laboratory Study of Venereal Disease As Neisseria gonorrhea in Male
Patients Over a 7 Month Period
3
Workload Data Base of Clinical Division Support in the Department of
Bacteriology and Clinical Laboratory Science
6
Prepartum Rectal Bacterial Flora; Phra Mongkutklao Hospital, Bangkok,
Thailand
8
Gibbon Release Program
10
Chemotherapy of Gnathostomiasis
14
Distribution of Rickettsia tsutsugamushi Strains in Thailand
19
Pathogens of Medically Important Mosquitoes of Thailand
21
Survey of Sylvatic Rodents for Serological Evidence of Rabies Virus
Infection
38
Animal Rabies in Thailand: Rabies Diagnostic Laboratory Services
40
A Survey of Viral Agents Transmitted by Culocoides in Northern Thailand
41
Leukocyte Subpopulations in Patients Infected with Dengue Hemorrhagic
Fever
42
Isolation of Dengue Virus from Patients in Provincial Hospitals
46
A Serological Survey for Togaviruses (Arboviruses) in a Well Defined
Rural Thai Population
48
A Longitudinal Epidemiological Study of Dengue Virus Infections in a
School Population
50
Isolation of Viruses from Leukocytes of Dengue Patients
55
Evaluation of Toxorhynchites splenens as a Bioassay Host for
Isolating Dengue Viruses
63
The Influence of Different Cell Culture Media on the Infectivity
Yield of Dengue Viruses
67
Glucose-6-Phosphate Dehydrogenase Deficiency and Dengue Hemorrhagic
73
Biological and Immunological Studies of a Dengue 2 Candidate Virus
Vaccine
76
Dengue Virus Isolation from Patients and Mosquitoes
82
Epidemiology of Hepatitis B in a Well Defined Rural Thai Population
84
A Longitudinal Study of Hepatitis B Virus Infection in a School Population
87
The Frequencies of Hepatitis B Antigen Subtypes in Various Parts of
90
The Prevalence of e-Antigen in Acute and Chronic Hepatitis in Thailand
92
The Epidemiology of Viral Hepatitis in Americans in Southeast Asia
95
The Prevalence of Hepatitis B Virus Markers in Dengue Hemorrhagic
Fever Patients
99
The Relationship Between Glucose-6-Phosphate Dehydrogenase
Deficiency and Hepatitis B Virus Infection
101
An Assessment of the Reverse Passive Hemagglutination as a Method
for the Detection of Hepatitis B Surface Antigen
103
Continuing Studies of Transmission of Hepatitis B Virus to Gibbons by
Exposure to Saliva Containing Hepatitis B Surface Antigen
106
Isolation of Influenza Viruses from Residents of Bangkok, Thailand
1976 -1977
112
Technical Training in the Department of Virology
113
Service Work of the Department of Virology
117
MALARIA STUDIES
The Suppression of Plasmodium falciparum and Plasmodium vivax
Parasitemias by Mef1oquine (WR 142490, a 4-Quinolinemethanol)
121
The Effect of Some Antimalarials on Gametocytogenesis and Sporogony
in Human Malaria in Thailand
127
P. falciparum Gametocytemia Following Schizonticidal Treatment
139
Single-Dose Therapy of Falciparum Malaria with Mefloquine or
Fansidar® (Pyrimethamine-Sulfadoxine)
143
Mefloquine Pharmacokinetics Following Oral Administration
147
In Vitro Chloroquine and Quinine Sensitivity of a Thai Strain of
Plasmodium falciparum
149
Evaluation of Experimental Antimalarial Drugs in Rhesus Monkeys
Infected with Plasmodium cynomolgi (Blood Schizonticidal Tests)
153
Evaluation of Experimental Antimalarial Drugs for Radical Curative
Activity in Rhesus Monkeys
155
Human Peripheral Blood Lymphocytes in Adults from Thailand with
Naturally Acquired Plasmodium falciparum and Plasmodium vivax
159
T Lymphocyte Subpopulations in Thai Malaria Patients
163
Production of Lymphokines and Chemotactic Activity of Malaria
Patient Monocytes
166
Circulating Lymphocytotoxic Factors in Malaria Patients
168
Mitogen Responsiveness of Lymphocytes from Patients Infected with
Malaria
170
Malaria Patient Lymphokine Mediated Macrophage Acitvation as
Demonstrated by Enchanced Adherence and Protein Synthesis
175
Glucosamine Uptake in Malaria Activated Human Macrophages
178
Transformation of Patient Lymphocytes by Selected Malaria Antigens
179
Synthesis of Lymphocyte Blastogenic Factor by Sensitized Lymphocytes
from Malaria Patients
182
In Vitro Gametogony of Plasmodium falciparum
184
Ecology of Malaria in Northern Thailand
186
PUBLICATION
193